A different form of hyaluronic acid
Profhilo® is composed of stabilised hyaluronic acid, but unlike traditional dermal fillers, it is not cross-linked to hold shape or projection.
Instead, it is designed to disperse within the tissue, spreading across the dermis rather than remaining in a fixed position.
This behaviour is central to its function. It does not create structure. It influences the environment in which the skin operates.
Hydration as a biological signal
Hyaluronic acid is inherently hydrophilic, meaning it attracts and retains water. When introduced into the skin, it increases hydration within the extracellular matrix, improving the conditions in which cells function. However, its role is not limited to moisture. Clinical observations show that this environment also supports:
• fibroblast activity
• collagen production
• elastin synthesis
This process, often described as bio-remodelling, allows the skin to gradually improve in elasticity and texture.
Distribution rather than placement
A defining feature of Profhilo® is how it is delivered. Rather than being placed throughout the skin in multiple small deposits, it is injected at specific anatomical points and allowed to diffuse. This controlled spread enables a more even effect across the treatment area, rather than a localised one. The outcome is therefore not a change in shape, but a change in skin quality as a whole.
Time as part of the mechanism
Unlike treatments that provide immediate structural change, bio-remodelling develops progressively. Hydration may be noticeable early, but improvements in elasticity and firmness emerge as collagen and elastin production increases. This reflects the biological nature of the process:
• stimulation occurs first
• structural change follows
The result is gradual, but integrated.