Cosmelan®

Cosmelan® is a professional depigmentation programme designed to reduce areas of uneven skin tone such as melasma, sun damage and post-inflammatory pigmentation. Unlike traditional peels, it works by regulating pigment production within the skin, helping to improve clarity and prevent recurrence over time. Because it is delivered as a structured treatment programme, consistency and aftercare play a key role in achieving and maintaining results.

Procedure

45 mins

Anaesthetic

None

Downtime

0-7 days

Duration

Permanent

Discomfort

Minimal

Treatments

1

Overview …

Cosmelan® is a medical-grade depigmentation treatment that targets the underlying causes of pigmentation, rather than focusing on surface-level colour alone.

It works by inhibiting the production of melanin within the skin, helping to reduce existing pigmentation while also limiting the formation of new pigment.

Cosmelan® is delivered as a programme rather than a single procedure, combining an in-clinic peel with a structured at-home regimen to achieve both short-term improvement and longer-term control.

This makes it particularly effective for persistent or hormonally driven pigmentation such as melasma.

Your Questions Answered ...

Six month programme:  £1800

At Mirabel, Cosmelan® is approached as a structured treatment programme, with equal emphasis placed on the in-clinic treatment and the homecare phase.

The aim is to:

• Reduce visible pigmentation in a controlled way
• Regulate melanin production within the skin
• Improve overall clarity and evenness of tone
• Support long-term management of pigmentation

Treatment is carefully guided throughout, with regular review points to monitor progress and adjust the programme where needed.

A consistent, staged approach is key to achieving meaningful and lasting results.

Cosmelan® is suitable for a range of pigmentation concerns, including:

• Melasma and hormonally influenced pigmentation
• Sun damage and age-related pigmentation
• Post-inflammatory pigmentation following acne or injury
• Uneven or patchy skin tone

It is suitable for all skin types and tones, making it a versatile option where some other treatments may be more limited.

Cosmelan® is delivered as a multi-step programme rather than a single treatment.

This typically includes:

Preparation phase – skin is prepared with targeted skincare prior to treatment
In-clinic treatment – a depigmentation mask is applied and left on for several hours
Early recovery phase – the skin may feel tight, red or begin to peel in the days following treatment
Homecare phase – a structured skincare routine is followed to regulate pigmentation long-term

Ongoing review appointments allow the programme to be adjusted as the skin responds.

The homecare phase is essential, as it helps to control melanin production and reduce the risk of recurrence.

Following treatment, it is common to experience:

• Redness and sensitivity
• Tightness or dryness
• Peeling or flaking of the skin over several days

These effects are expected and form part of the skin renewal process.

Visible improvement often begins within the first few weeks, although continued improvement depends on adherence to the homecare programme.

Results from Cosmelan® depend on several factors:

• Consistency with the homecare programme
• Ongoing sun protection
• The type and depth of pigmentation
• Hormonal influences

Because pigmentation can be triggered by multiple factors, long-term management is often required to maintain results.

Our Practitioners ...

Rena Jarman Aesthetician Mirabel Clinic

Rena Jarman

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